Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27002444 | 0.88 | AR (0.34) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581278 | 0.88 | ADORA1 (0.33) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581297 | 0.85 | PRMT5 (0.36) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25218581 | 0.83 | ADORA1 (0.31) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581256 | 0.79 | POLB (0.51) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30752917 | 0.77 | ADORA1 (0.32) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL23087910 | 0.76 | ADORA1 (0.53) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31222758 | 0.74 | PRMT5 (0.32) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581234 | 0.74 | PRMT5 (0.35) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL23087286 | 0.73 | ADORA1 (0.39) | ADORA1PDE1APDE1BPDE3BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098439-A1 | PYRAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 上海和誉生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |