Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752835 | 0.90 | ADORA1 (0.41) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30752986 | 0.83 | ADORA1 (0.43) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581275 | 0.77 | ADORA1 (0.38) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL27002444 | 0.76 | AR (0.34) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581278 | 0.76 | ADORA1 (0.33) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581297 | 0.74 | PRMT5 (0.36) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31496890 | 0.73 | ADORA1 (0.38) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25218581 | 0.71 | ADORA1 (0.31) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31222760 | 0.70 | ADORA1 (0.32) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30753040 | 0.70 | PDPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024027703-A1 | PRMT5 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-02-08 | — | — | WO | disclosed |