Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 7/20 | 0.45 |
| ▸ | CCNH | P51946 | 7/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.42 |
| ▸ | CDK2 | P24941 | 7/20 | 0.42 |
| ▸ | CCNK | O75909 | 6/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.42 |
| ▸ | CDK9 | P50750 | 5/20 | 0.42 |
| ▸ | EGFR | P00533 | 9/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25581306 | 0.92 | PTK2 (0.46) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581309 | 0.90 | CDK7 (0.43) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581307 | 0.90 | CDK7 (0.45) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581345 | 0.89 | CDK7 (0.43) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25596598 | 0.89 | CCNE1 (0.44) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581308 | 0.88 | CDK7 (0.47) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581347 | 0.85 | CDK7 (0.39) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581466 | 0.83 | PTK2 (0.45) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25581352 | 0.82 | CCNE1 (0.41) | CDK7CCNHCCNE1CDK2CCNK | |
| SCHEMBL25580553 | 0.82 | BTK (0.46) | CDK7CCNHCCNE1CDK2CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078451-A1 | COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-05-11 | — | — | WO | disclosed |