Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 14/20 | 0.44 |
| ▸ | CCNK | O75909 | 14/20 | 0.44 |
| ▸ | CDK9 | P50750 | 14/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.44 |
| ▸ | CDK7 | P50613 | 5/20 | 0.44 |
| ▸ | CCNH | P51946 | 5/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.44 |
| ▸ | CDK2 | P24941 | 13/20 | 0.44 |
| ▸ | FLT3 | P36888 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25581372 | 0.96 | CCNK (0.47) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25581373 | 0.96 | CCNK (0.47) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25581444 | 0.92 | CDK7 (0.44) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25580832 | 0.90 | CCNT1 (0.51) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25581370 | 0.89 | CCNK (0.45) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25581371 | 0.89 | CCNK (0.45) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25581375 | 0.89 | CCNT1 (0.53) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25583399 | 0.88 | CCNT1 (0.48) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25581369 | 0.88 | CDK7 (0.40) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25583408 | 0.88 | CCNK (0.42) | CCNT1CCNKCDK9CDK12CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078451-A1 | COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-05-11 | — | — | WO | disclosed |