Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 10/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 10/20 | 0.42 |
| ▸ | CDK7 | P50613 | 6/20 | 0.42 |
| ▸ | CCNH | P51946 | 6/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.39 |
| ▸ | CDK9 | P50750 | 7/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.39 |
| ▸ | CDK2 | P24941 | 7/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25581366 | 0.88 | CCNT1 (0.44) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25581444 | 0.86 | CDK7 (0.44) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25581373 | 0.85 | CCNK (0.47) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25581372 | 0.85 | CCNK (0.47) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25594065 | 0.85 | CDK7 (0.47) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25596475 | 0.85 | CDK7 (0.47) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25595353 | 0.83 | CDK7 (0.43) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25581447 | 0.83 | CCNK (0.41) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25581370 | 0.83 | CCNK (0.45) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25581371 | 0.83 | CCNK (0.45) | CCNKCDK12CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078451-A1 | COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-05-11 | — | — | WO | disclosed |