SCHEMBL25581463 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	LCK	P06239	1/20	0.40

▸	CCNK	O75909	15/20	0.39

▸	CDK12	Q9NYV4	15/20	0.39

▸	CCNE1	P24864	14/20	0.39

▸	CDK2	P24941	14/20	0.39

▸	CCNT1	O60563	12/20	0.39

▸	CDK9	P50750	12/20	0.39

▸	CDK7	P50613	10/20	0.38

▸	CCNH	P51946	10/20	0.38

▸	MNAT1	P51948	6/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25581354	0.95	LCK (0.41)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25583393	0.94	LCK (0.40)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25581351	0.93	LCK (0.39)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25581350	0.91	CCNK (0.39)	CCNKCDK12CCNE1CDK2CCNT1
SCHEMBL25581443	0.90	LCK (0.41)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25581286	0.89	LCK (0.47)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25580806	0.86	JAK1 (0.45)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25580809	0.84	JAK1 (0.46)	LCKCCNKCDK12CCNE1CDK2
SCHEMBL25581352	0.83	CCNE1 (0.41)	CCNKCDK12CCNE1CDK2CCNT1
SCHEMBL25581348	0.83	CCNK (0.39)	CCNKCDK12CCNE1CDK2CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023078451-A1	COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF	浙江同源康医药股份有限公司	2023-05-11	—	—	WO	disclosed