Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229888 | 0.76 | CYP1A2 (0.38) | TSHR | |
| SCHEMBL29617181 | 0.76 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL29617180 | 0.76 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL29617173 | 0.74 | FAAH (0.41) | TSHRALDH1A1 | |
| SCHEMBL17982757 | 0.74 | TSHR (0.45) | TSHRENPP1ALDH1A1 | |
| SCHEMBL17982758 | 0.74 | TSHR (0.45) | TSHRENPP1ALDH1A1 | |
| SCHEMBL30002745 | 0.73 | TSHR (0.55) | TSHRENPP1ALDH1A1 | |
| SCHEMBL29617152 | 0.72 | FAAH (0.45) | — | |
| SCHEMBL9421757 | 0.72 | TSHR (0.30) | TSHRALDH1A1 | |
| SCHEMBL9421755 | 0.72 | TSHR (0.30) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382240-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | Bridgestone Corporation (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085622-A9 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010085622-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |