Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23487511 | 0.89 | MEN1 (0.46) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL22399456 | 0.81 | MEN1 (0.44) | KDM4EMEN1KMT2ATSHRTK1 | |
| SCHEMBL25781533 | 0.80 | TK1 (0.58) | KDM4EMEN1KMT2ATSHRTK1 | |
| SCHEMBL22571148 | 0.78 | MEN1 (0.52) | KDM4EMEN1KMT2ATSHRTK1 | |
| SCHEMBL22907647 | 0.78 | MEN1 (0.42) | KDM4EMEN1KMT2ATSHRTK1 | |
| SCHEMBL3457921 | 0.76 | MEN1 (0.50) | KDM4EMEN1KMT2ATSHRTK1 | |
| SCHEMBL16310639 | 0.76 | MEN1 (0.42) | KDM4EMEN1KMT2ATSHRTK1 | |
| SCHEMBL22875772 | 0.76 | MEN1 (0.64) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL26230855 | 0.76 | MEN1 (0.46) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL5930447 | 0.75 | MEN1 (0.60) | KDM4EMEN1KMT2ATSHRTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |