Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 6/20 | 0.40 |
| ▸ | CHUK | O15111 | 3/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25584605 | 0.93 | MKNK1 (0.41) | IKBKBCHUKSSTR4CHRNB2CHRNA4 | |
| SCHEMBL8271735 | 0.88 | IKBKB (0.55) | IKBKBCHUKCHRNB2CHRNA4ROCK1 | |
| Hydrochloric Acid SCHEMBL4120289 | 0.87 | IKBKB (0.53) | IKBKBCHUKCHRNB2CHRNA4ROCK1 | |
| SCHEMBL14239774 | 0.86 | IKBKB (0.50) | IKBKBCHUKCHRNB2CHRNA4ROCK1 | |
| SCHEMBL23021681 | 0.85 | CHRNB2 (0.47) | IKBKBCHUKSSTR4CHRNB2CHRNA4 | |
| SCHEMBL4123852 | 0.81 | IKBKB (0.50) | IKBKBCHUKSSTR4GPR119 | |
| SCHEMBL22051458 | 0.77 | IKBKB (0.50) | IKBKBCHUKROCK1LCKROCK2 | |
| SCHEMBL22040965 | 0.77 | IKBKB (0.40) | IKBKBCHUKROCK1LCKROCK2 | |
| SCHEMBL31342868 | 0.77 | IKBKB (0.40) | IKBKBCHUKROCK1LCKROCK2 | |
| SCHEMBL22041246 | 0.77 | IKBKB (0.38) | IKBKBCHUKROCK1LCKROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |