SCHEMBL25585064

SCHEMBL25585064

Clc1ccc2c(c1)c1c(-c3ccc(-c4ccccc4)cc3)cccc1n2-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 1/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ EDNRA P25101 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ PTGES O14684 1/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37
▸ MDM2 Q00987 1/20 0.36
▸ PTGDR2 Q9Y5Y4 1/20 0.36
▸ HDAC4 P56524 1/20 0.36
▸ ADORA2B P29275 1/20 0.35
▸ FGFR1 P11362 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ JAK2 O60674 1/20 0.34
▸ JAK3 P52333 1/20 0.34
▸ AURKA O14965 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25584693 1.00 MAPK14 (0.39) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL19997884 1.00 MAPK14 (0.39) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL25584763 0.97 MAPK14 (0.38) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL19997910 0.97 MEN1 (0.42) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL25583917 0.95 L3MBTL1 (0.37) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL19997886 0.94 MEN1 (0.43) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL25583955 0.94 JAK2 (0.41) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL25585066 0.92 MAPK14 (0.38) MAPK14L3MBTL1MEN1KMT2ALMNA
SCHEMBL25583918 0.91 PPARG (0.43) MAPK14EDNRAPTGESMDM2PTGDR2
SCHEMBL26191632 0.91 L3MBTL1 (0.40) MAPK14L3MBTL1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023070987-A9 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2023-08-24 — — WO disclosed
US-20230247903-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS INCLUDING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-03 — — US disclosed
US-20230247903-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS INCLUDING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-03 — — US disclosed
EP-4198020-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2023-06-21 — — EP disclosed
WO-2023087557-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-05-25 — — WO disclosed
WO-2023070987-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2023-05-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247903-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS INCLUDING SAME OR10J3, ODC1, ORC3 MAPK14 2748/4885L3MBTL1 1729/4885MEN1 1248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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