SCHEMBL2558520

SCHEMBL2558520

ClC(Cl)(Cl)N1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP2B6 P20813 1/20 0.32
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10579837 0.96
SCHEMBL28571890 0.81
Hydrochloric Acid SCHEMBL8479541 0.71 MEN1 (0.39) MEN1KMT2ACYP2B6
SCHEMBL10993369 0.67
SCHEMBL28971409 0.67 ADRB1 (0.31)
SCHEMBL494457 0.65
SCHEMBL24927970 0.64 CYP2B6 (0.42) CYP2B6MGLL
SCHEMBL23988087 0.64 CYP2B6 (0.42) CYP2B6MGLL
SCHEMBL696562 0.64 CYP2B6 (0.32) CYP2B6MGLL
SCHEMBL24928198 0.64 CYP2B6 (0.42) CYP2B6MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109517142-A Star-like D-A structure conjugated molecule and its preparation method and application based on five yuan of heteroaromatics of trimerization indeno 中国科学院长春应用化学研究所 2019-03-26 CN disclosed
CN-102603611-B Preparation method of trifluoromethyl piperidine compounds JUHUA GROUP CORP 2014-05-07 CN disclosed
EP-2556076-A2 NOVEL SULTAM COMPOUNDS Pfizer Inc. (US) 2013-02-13 EP disclosed
CN-102603611-A Preparation method of trifluoromethyl piperidine compounds JUHUA GROUP CORP 2012-07-25 CN disclosed
WO-2011125006-A2 NOVEL SULTAM COMPOUNDS PFIZER INC. (US) 2011-10-13 WO disclosed