Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735200 | 0.85 | TSHR (0.54) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL9509274 | 0.81 | TSHR (0.55) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL4589846 | 0.81 | TSHR (0.55) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL8417277 | 0.79 | TSHR (0.52) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL23352573 | 0.78 | TSHR (0.47) | TSHRHSD17B10KMT2ALMNAALDH1A1 | |
| SCHEMBL22804532 | 0.78 | TSHR (0.48) | TSHRKMT2ALMNAALDH1A1CA12 | |
| SCHEMBL112204 | 0.77 | TSHR (0.63) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL284589 | 0.77 | TSHR (0.63) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL11960809 | 0.76 | TSHR (0.48) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL857398 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3391941-B1 | NOVEL CELL-PERMEABLE SUCCINATE COMPOUNDS | Abliva Ab (SE) | 2023-06-07 | — | — | EP | disclosed |