Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL11493762 | 0.90 | TSHR (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL22500800 | 0.86 | TSHR (0.58) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL10353009 | 0.85 | TSHR (0.56) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL3490443 | 0.83 | ALDH1A1 (0.46) | TSHRCYP2C19POLBBLMATM | |
| SCHEMBL28547678 | 0.83 | TSHR (0.54) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL8427111 | 0.83 | TSHR (0.54) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL9509274 | 0.81 | TSHR (0.55) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL17072460 | 0.80 | TSHR (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8417277 | 0.79 | TSHR (0.52) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL15743418 | 0.78 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| US-9579404-B2 | Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof | NEW YORK UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150071863-A1 | LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF | UNIV NEW YORK (US) | 2015-03-12 | — | — | US | disclosed |
| US-8865129-B2 | Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof | NEW YORK UNIVERSITY (US) | 2014-10-21 | — | — | US | disclosed |
| US-20120294809-A1 | LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF | NEW YORK UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| EP-1937656-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS BETA 2 ADRENOCEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007027134-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150071863-A1 | LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF | LIPA, LPXN, LIPC | TSHR 579/4885HSD17B10 2160/4885MGAM 1583/4885 |
| US-20120294809-A1 | LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF | LIPA, LPXN, LIPC | TSHR 579/4885HSD17B10 2160/4885MGAM 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.