Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16194556 | 0.84 | KMT2A (0.47) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL17295091 | 0.82 | KMT2A (0.46) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL31626601 | 0.82 | KMT2A (0.49) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL31626656 | 0.82 | SMN1; SMN2 (0.54) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL31626509 | 0.82 | SMN1; SMN2 (0.70) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL16221641 | 0.81 | SMN1; SMN2 (0.56) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL4826104 | 0.81 | KMT2A (0.64) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL869929 | 0.80 | PTGS2 (0.63) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL15330061 | 0.80 | GAA (0.69) | KMT2AMEN1NLRP3LMNAMAPT | |
| SCHEMBL15330287 | 0.79 | KMT2A (0.58) | KMT2AMEN1NLRP3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |