Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12000236 | 0.84 | MAPT (0.58) | GRM1KMT2ARXFP1MAPTNPSR1 | |
| SCHEMBL667729 | 0.82 | GRM1 (0.46) | GRM1KMT2ARXFP1PSMB5MAPT | |
| SCHEMBL21550243 | 0.81 | KMT2A (0.44) | KMT2ARXFP1PDE3BPDE3AMAPT | |
| SCHEMBL12000237 | 0.80 | ALDH1A1 (0.59) | GRM1KMT2ARXFP1PDE3BPDE3A | |
| SCHEMBL8735682 | 0.79 | KMT2A (0.70) | GRM1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL15358899 | 0.79 | KMT2A (0.42) | KMT2ARXFP1PDE3BPDE3AMAPT | |
| SCHEMBL6365630 | 0.77 | KDM4E (0.45) | GRM1KMT2ARXFP1MAPTALDH1A1 | |
| SCHEMBL13227193 | 0.76 | MAPT (0.51) | KMT2ARXFP1MAPTNPSR1KDM4E | |
| SCHEMBL13136437 | 0.76 | MAPT (0.51) | GRM1KMT2ARXFP1PSMB5MAPT | |
| SCHEMBL8352244 | 0.76 | CYP1A2 (0.56) | GRM1KMT2APDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733662-B1 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |