Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892980 | 0.87 | NOTUM (0.69) | NOTUMMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL24435477 | 0.87 | NOTUM (0.69) | NOTUMMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1221442 | 0.84 | MAPT (0.65) | NOTUMMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28087158 | 0.79 | NOTUM (0.56) | NOTUMMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL25603132 | 0.78 | NOTUM (0.53) | NOTUMMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL20046283 | 0.75 | USP2 (0.57) | NOTUMMAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL20887690 | 0.74 | MAPT (0.57) | NOTUMMAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL19904630 | 0.74 | MAPT (0.57) | NOTUMMAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL22434593 | 0.74 | MAPT (0.57) | NOTUMMAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL20887605 | 0.74 | MAPT (0.57) | NOTUMMAPTALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |