Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 8/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | BTK | Q06187 | 6/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992127 | 0.91 | FGFR4 (0.39) | ERBB2MAP2K7EGFRBTKFGFR1 | |
| SCHEMBL25589069 | 0.88 | BTK (0.36) | ERBB2MAP2K7EGFRBTKFGFR1 | |
| SCHEMBL25589070 | 0.86 | MAP2K7 (0.35) | ERBB2MAP2K7EGFRBTKCTSC | |
| SCHEMBL25589067 | 0.86 | MAP2K7 (0.35) | ERBB2MAP2K7EGFRBTKCTSC | |
| SCHEMBL25597424 | 0.85 | MAP2K7 (0.37) | MAP2K7EGFRBTKFGFR4CTSC | |
| SCHEMBL25589708 | 0.85 | ERBB2 (0.40) | ERBB2MAP2K7EGFRBTKCTSC | |
| SCHEMBL25597420 | 0.85 | BTK (0.35) | ERBB2MAP2K7EGFRBTKCTSC | |
| SCHEMBL24992584 | 0.85 | FGFR1 (0.38) | ERBB2MAP2K7EGFRBTKFGFR1 | |
| SCHEMBL25598057 | 0.85 | BTK (0.36) | ERBB2MAP2K7EGFRBTKFGFR1 | |
| SCHEMBL25589193 | 0.85 | FGFR4 (0.39) | ERBB2MAP2K7EGFRBTKFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078413-A1 | FGFR2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-05-11 | — | — | WO | disclosed |