Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25589046 | 1.00 | CRBN (0.62) | CRBNDDB1ADORA2AADORA1HTR7 | |
| SCHEMBL31334106 | 0.90 | DDB1 (0.56) | CRBNDDB1ADORA2AADORA1 | |
| SCHEMBL30135966 | 0.87 | CRBN (0.55) | CRBNDDB1CHEK1AURKACHEK2 | |
| SCHEMBL30738802 | 0.85 | DDB1 (0.61) | CRBNDDB1 | |
| SCHEMBL27178975 | 0.85 | DDB1 (0.61) | CRBNDDB1 | |
| SCHEMBL31334544 | 0.84 | DDB1 (0.48) | CRBNDDB1SMN1; SMN2 | |
| SCHEMBL38657472 | 0.83 | DDB1 (0.67) | CRBNDDB1CHEK1AURKACHEK2 | |
| Hydrochloric Acid SCHEMBL31554745 | 0.82 | DDB1 (0.66) | CRBNDDB1CHEK1AURKACHEK2 | |
| SCHEMBL24125507 | 0.82 | DDB1 (0.58) | CRBNDDB1 | |
| SCHEMBL31323688 | 0.82 | DDB1 (0.58) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |