SCHEMBL38657472

SCHEMBL38657472

Cn1nc(N2CCC(=O)NC2=O)c2ccc(N3CCC(N)CC3)cc21

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 13/20 0.67
CRBN Q96SW2 13/20 0.67
KHK P50053 1/20 0.39
HTR6 P50406 5/20 0.36
HTR2B P41595 4/20 0.36
CHEK1 O14757 1/20 0.35
AURKA O14965 1/20 0.35
CHEK2 O96017 1/20 0.35
ABL1 P00519 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
LYN P07948 1/20 0.35
SRC P12931 1/20 0.35
CSNK1D P48730 1/20 0.35
MAPKAPK2 P49137 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31554745 0.99 DDB1 (0.66) DDB1CRBNKHKHTR6HTR2B
SCHEMBL38657940 0.88 DDB1 (0.65) DDB1CRBN
SCHEMBL25448885 0.88 CRBN (0.62) DDB1CRBNKHK
SCHEMBL25586560 0.88 CRBN (0.62) DDB1CRBNKHK
SCHEMBL30810470 0.88 CRBN (0.62) DDB1CRBNKHK
SCHEMBL23538519 0.87 CRBN (0.69) DDB1CRBNKHKHTR6CHEK1
SCHEMBL24873284 0.87 DDB1 (0.69) DDB1CRBNKHKHTR6CHEK1
Hydrochloric Acid SCHEMBL31520848 0.87 DDB1 (0.64) DDB1CRBN
SCHEMBL30738802 0.87 DDB1 (0.61) DDB1CRBNKHK
SCHEMBL30822474 0.87 DDB1 (0.61) DDB1CRBNKHKAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102147-A1 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS Treeline Biosciences, Inc. (US) 2026-05-15 WO disclosed