Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 3/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 6/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | YES1 | P07947 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | FGR | P09769 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CSK | P41240 | 1/20 | 0.45 |
| ▸ | BLK | P51451 | 1/20 | 0.45 |
| ▸ | BMX | P51813 | 1/20 | 0.45 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590772 | 0.89 | ABL1 (0.49) | CSF1RKITBRAFRAF1ABL1 | |
| SCHEMBL25590776 | 0.88 | ABL1 (0.46) | CSF1RKITBRAFRAF1ABL1 | |
| SCHEMBL25590395 | 0.88 | IDO1 (0.48) | CSF1RKITABL1NPC1RAB9A | |
| SCHEMBL25590895 | 0.88 | CLK2 (0.44) | CSF1RKITABL1FYNLYN | |
| SCHEMBL25590681 | 0.87 | GSK3B (0.46) | CSF1RABL1BCRTRPV1MCHR1 | |
| SCHEMBL25592195 | 0.87 | CSF1R (0.45) | CSF1RKITBRAFRAF1ABL1 | |
| SCHEMBL25590905 | 0.87 | ABL1 (0.42) | CSF1RABL1BCRTRPV1MCHR1 | |
| SCHEMBL25591482 | 0.87 | FGFR1 (0.44) | CSF1RABL1BCRTRPV1MCHR1 | |
| SCHEMBL25590907 | 0.87 | HIF1A (0.46) | CSF1RABL1BCRTRPV1MCHR1 | |
| SCHEMBL25247883 | 0.86 | MCHR1 (0.48) | CSF1RKITBRAFRAF1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |