Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | CSF1R | P07333 | 8/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.46 |
| ▸ | BRAF | P15056 | 3/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CSK | P41240 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590396 | 0.88 | CSF1R (0.53) | ABL1CSF1RKITBRAFRAF1 | |
| SCHEMBL25593891 | 0.87 | GSK3B (0.45) | TRPV1CLK2CLK3DYRK1A | |
| SCHEMBL25590395 | 0.87 | IDO1 (0.48) | ABL1CSF1RKITAURKBCLK2 | |
| SCHEMBL25590895 | 0.87 | CLK2 (0.44) | ABL1CSF1RKITAURKAAURKB | |
| SCHEMBL25590389 | 0.85 | NPC1 (0.47) | CSF1RKITAURKAAURKBCLK2 | |
| SCHEMBL25590401 | 0.85 | AURKB (0.52) | ABL1CSF1RKITAURKAAURKB | |
| SCHEMBL25590393 | 0.82 | EP300 (0.46) | KITCLK2 | |
| SCHEMBL25591365 | 0.82 | MAOB (0.47) | ABL1CSF1RKITBRAFRAF1 | |
| SCHEMBL25590684 | 0.82 | GSK3B (0.49) | ABL1AURKAAURKBCLK2DYRK1A | |
| SCHEMBL25590786 | 0.81 | MAPT (0.48) | CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |