⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590843 | 0.89 | — | — | |
| SCHEMBL22803217 | 0.77 | — | — | |
| SCHEMBL22803215 | 0.72 | ALPL (0.32) | — | |
| SCHEMBL25590831 | 0.70 | CRBN (0.30) | — | |
| SCHEMBL25590834 | 0.68 | MAP4K1 (0.38) | — | |
| SCHEMBL22803490 | 0.62 | — | — | |
| SCHEMBL22803218 | 0.61 | MAP4K1 (0.40) | — | |
| SCHEMBL22803132 | 0.60 | MAP4K1 (0.42) | — | |
| SCHEMBL25591664 | 0.59 | MAP4K1 (0.31) | — | |
| SCHEMBL22803430 | 0.59 | NR3C2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037342-B2 | Substituted eneoxindoles and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230183262-A1 | SUBSTITUTED ENEOXINDOLES AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |