Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 18/20 | 0.56 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.56 |
| ▸ | CDK2 | P24941 | 15/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.56 |
| ▸ | CDK9 | P50750 | 15/20 | 0.56 |
| ▸ | CDK7 | P50613 | 12/20 | 0.56 |
| ▸ | CCNH | P51946 | 12/20 | 0.56 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25591998 | 0.95 | CCNK (0.58) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25594838 | 0.93 | CCNK (0.61) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25594834 | 0.93 | CCNK (0.61) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25594867 | 0.90 | CCNK (0.58) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25592234 | 0.90 | CCNK (0.58) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25594756 | 0.88 | CCNT1 (0.59) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25592233 | 0.88 | CCNK (0.59) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25594853 | 0.88 | CCNK (0.59) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25595553 | 0.87 | CCNK (0.62) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25595555 | 0.87 | CCNK (0.62) | CCNKCDK12CCNE1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295130-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | TYK MEDICINES, INC. (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-4186895-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | TYK Medicines Inc. (CN) | 2023-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295130-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | CDK7, CDK6, CDK9 | CCNK 15/4885CDK12 27/4885CCNE1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.