Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | MAOB | P27338 | 4/20 | 0.71 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941947 | 0.87 | MRGPRX4 (0.70) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL2555133 | 0.87 | MAOA (0.73) | MAOAMAOBNR4A2PKMSMN1; SMN2 | |
| SCHEMBL29953186 | 0.87 | MRGPRX4 (0.70) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL31482043 | 0.87 | MAOA (0.73) | MAOAMAOBNR4A2PKMSMN1; SMN2 | |
| SCHEMBL4406160 | 0.87 | NR4A2 (0.87) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL9368875 | 0.85 | MRGPRX4 (0.66) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL9369666 | 0.85 | MRGPRX4 (0.69) | MAOAMAOBMRGPRX4TP53PKM | |
| SCHEMBL314161 | 0.84 | MAOB (1.00) | MAOAMAOBPKMRAB9A | |
| SCHEMBL4138759 | 0.84 | NR4A2 (0.81) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL29454637 | 0.84 | MAOB (1.00) | MAOAMAOBPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |