Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590474 | 0.87 | ATR (0.51) | ABL1MAPTKMT2AATRNPC1 | |
| SCHEMBL25590579 | 0.85 | ABL1 (0.45) | ABL1MAPTMEN1KMT2ATRPV1 | |
| SCHEMBL25591776 | 0.84 | ABL1 (0.50) | ABL1MAPTTRPV1LMNANPC1 | |
| SCHEMBL25590383 | 0.84 | ATR (0.49) | ABL1MAPTMEN1KMT2ATRPV1 | |
| SCHEMBL25590566 | 0.83 | NPC1 (0.49) | MAPTMEN1KMT2ATRPV1LMNA | |
| SCHEMBL25590564 | 0.83 | ROCK1 (0.48) | MAPTTRPV1LMNANPC1GMNN | |
| SCHEMBL25590568 | 0.82 | ABL1 (0.47) | ABL1MAPTMEN1KMT2AATR | |
| SCHEMBL25590396 | 0.82 | CSF1R (0.53) | ABL1MAPTTRPV1LMNANPC1 | |
| SCHEMBL25590905 | 0.82 | ABL1 (0.42) | ABL1MAPTTRPV1LMNANPC1 | |
| SCHEMBL25590481 | 0.81 | SMN1; SMN2 (0.47) | ABL1MAPTMEN1KMT2AATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |