Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.55 |
| ▸ | BTK | Q06187 | 9/20 | 0.55 |
| ▸ | JAK3 | P52333 | 15/20 | 0.49 |
| ▸ | EGFR | P00533 | 9/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25593537 | 0.97 | LCK (0.55) | LCKBTKJAK3EGFRSYK | |
| SCHEMBL24891041 | 0.84 | LCK (0.49) | LCKBTKJAK3EGFRSYK | |
| SCHEMBL30195945 | 0.84 | JAK3 (0.47) | LCKBTKJAK3EGFR | |
| SCHEMBL21947753 | 0.84 | JAK3 (0.47) | LCKBTKJAK3EGFR | |
| SCHEMBL25593703 | 0.84 | JAK3 (0.75) | LCKBTKJAK3EGFR | |
| SCHEMBL18296155 | 0.83 | LCK (0.73) | LCKBTKJAK3EGFRSYK | |
| SCHEMBL25595883 | 0.83 | SYK (0.50) | LCKBTKJAK3EGFRSYK | |
| SCHEMBL24891043 | 0.83 | LCK (0.47) | LCKBTKJAK3EGFRSYK | |
| SCHEMBL25593539 | 0.82 | BTK (0.49) | LCKBTKJAK3EGFR | |
| SCHEMBL25649437 | 0.82 | JAK3 (0.57) | LCKBTKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |