Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 11/20 | 0.47 |
| ▸ | BTK | Q06187 | 11/20 | 0.47 |
| ▸ | JAK3 | P52333 | 12/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891043 | 0.96 | LCK (0.47) | SYKLCKBTKJAK3EGFR | |
| SCHEMBL25593539 | 0.92 | BTK (0.49) | LCKBTKJAK3EGFR | |
| SCHEMBL25593537 | 0.84 | LCK (0.55) | SYKLCKBTKJAK3EGFR | |
| SCHEMBL25593403 | 0.83 | LCK (0.55) | SYKLCKBTKJAK3EGFR | |
| SCHEMBL25593916 | 0.83 | JAK3 (0.72) | LCKBTKJAK3EGFR | |
| SCHEMBL24833229 | 0.81 | JAK3 (0.64) | LCKBTKJAK3EGFR | |
| SCHEMBL21947753 | 0.81 | JAK3 (0.47) | LCKBTKJAK3EGFR | |
| SCHEMBL30195945 | 0.81 | JAK3 (0.47) | LCKBTKJAK3EGFR | |
| SCHEMBL21946277 | 0.79 | JAK3 (0.72) | LCKBTKJAK3EGFR | |
| SCHEMBL31039897 | 0.79 | JAK3 (0.72) | LCKBTKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |