Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 20/20 | 0.77 |
| ▸ | CDK12 | Q9NYV4 | 20/20 | 0.77 |
| ▸ | CCNT1 | O60563 | 19/20 | 0.77 |
| ▸ | CDK9 | P50750 | 19/20 | 0.77 |
| ▸ | CDK7 | P50613 | 7/20 | 0.77 |
| ▸ | CCNH | P51946 | 7/20 | 0.77 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.72 |
| ▸ | CDK2 | P24941 | 16/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25591866 | 0.90 | CCNK (0.72) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL24840741 | 0.87 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL24839365 | 0.84 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL25594546 | 0.83 | CCNT1 (0.69) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL25596018 | 0.82 | CCNT1 (0.67) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL24839364 | 0.82 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL25591782 | 0.80 | CCNT1 (0.65) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL31666667 | 0.80 | CCNK (0.70) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL30927751 | 0.80 | CCNK (0.70) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL25594753 | 0.80 | CCNT1 (0.64) | CCNKCDK12CCNT1CDK9CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186895-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | TYK Medicines Inc. (CN) | 2023-05-31 | — | — | EP | disclosed |