Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554070 | 0.86 | MRGPRX4 (0.68) | MRGPRX4ENPP2SMN1; SMN2 | |
| SCHEMBL2556265 | 0.86 | MRGPRX4 (0.61) | MRGPRX4ENPP2FFAR1FFAR4 | |
| SCHEMBL2554749 | 0.85 | MRGPRX4 (0.53) | MRGPRX4ENPP2FFAR1FFAR4SCN4A | |
| SCHEMBL2555006 | 0.83 | MRGPRX4 (0.61) | MRGPRX4ENPP2THRBSMN1; SMN2 | |
| SCHEMBL2558750 | 0.83 | MRGPRX4 (0.64) | MRGPRX4ENPP2FFAR1FFAR4 | |
| SCHEMBL6833481 | 0.82 | ENPP2 (0.52) | MRGPRX4ENPP2FFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL2558808 | 0.81 | MRGPRX4 (0.63) | MRGPRX4ENPP2SMN1; SMN2 | |
| SCHEMBL13144443 | 0.79 | MRGPRX4 (0.68) | MRGPRX4FFAR1FFAR4SCN4A | |
| SCHEMBL2557599 | 0.79 | ENPP2 (0.51) | MRGPRX4ENPP2 | |
| SCHEMBL2561245 | 0.79 | ENPP2 (0.64) | MRGPRX4ENPP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |