Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566704 | 0.85 | CRBN (0.63) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL25567340 | 0.84 | CRBN (0.72) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL24753305 | 0.84 | CRBN (0.65) | CRBNDDB1 | |
| SCHEMBL25567342 | 0.82 | CRBN (0.54) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL26329782 | 0.79 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL31639917 | 0.79 | CRBN (0.56) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL25229932 | 0.78 | CRBN (0.55) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL25223993 | 0.78 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL29535683 | 0.78 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL24752738 | 0.77 | CRBN (0.60) | CRBNDDB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |