Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566705 | 0.85 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL23551579 | 0.77 | CRBN (0.77) | CRBNDDB1 | |
| SCHEMBL25566704 | 0.75 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL26826457 | 0.75 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL30258522 | 0.75 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL26621484 | 0.74 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL25023330 | 0.74 | CRBN (0.70) | CRBNDDB1 | |
| SCHEMBL25026932 | 0.74 | CRBN (0.77) | CRBNDDB1 | |
| SCHEMBL24126163 | 0.73 | CRBN (0.76) | CRBNDDB1 | |
| SCHEMBL29640977 | 0.73 | CRBN (0.76) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |