Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25502728 | 0.95 | PDK2 (0.41) | PDK2 | |
| SCHEMBL3885909 | 0.82 | PDK2 (0.49) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL22744936 | 0.82 | PDK2 (0.49) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL29456661 | 0.82 | PDK2 (0.49) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL17780753 | 0.81 | PDK2 (0.46) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL29399278 | 0.80 | PDK2 (0.58) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL996751 | 0.80 | PDK2 (0.58) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL783450 | 0.80 | PDK2 (0.58) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL29574412 | 0.80 | PDK2 (0.58) | PDK2PTPRCESR1ESR2OPRM1 | |
| SCHEMBL783463 | 0.80 | PDK2 (0.58) | PDK2PTPRCESR1ESR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099543-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2023-06-08 | — | — | WO | disclosed |