Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 8/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | SORD | Q00796 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593659 | 0.84 | EDNRB (0.46) | EDNRBEDNRAKMT2AMEN1RAB9A | |
| SCHEMBL29370636 | 0.84 | EDNRB (0.46) | EDNRBEDNRAKMT2AMEN1RAB9A | |
| SCHEMBL25211129 | 0.78 | RXRA (0.45) | EDNRBEDNRAKMT2AMEN1RAB9A | |
| SCHEMBL31174746 | 0.78 | RXRA (0.45) | EDNRBEDNRAKMT2AMEN1RAB9A | |
| SCHEMBL1153496 | 0.77 | — | — | |
| SCHEMBL30125106 | 0.77 | — | — | |
| SCHEMBL23978003 | 0.77 | EDNRB (0.44) | EDNRBEDNRAKMT2AMEN1RAB9A | |
| SCHEMBL26705487 | 0.73 | RXRA (0.40) | EDNRBEDNRAKMT2AMEN1RAB9A | |
| SCHEMBL7049033 | 0.71 | — | — | |
| SCHEMBL8154440 | 0.69 | MAPK8 (0.41) | EDNRBEDNRARXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078413-A1 | FGFR2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-05-11 | — | — | WO | disclosed |