Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106840 | 0.73 | ALDH1A1 (0.43) | EPHX2ALDH1A1LMNAGRM5NPC1 | |
| SCHEMBL22198327 | 0.72 | ALDH1A1 (0.40) | IGF1REPHX2ALDH1A1LMNAGRM5 | |
| SCHEMBL25138308 | 0.71 | EPHX2 (0.32) | IGF1REPHX2ALDH1A1LMNA | |
| SCHEMBL22837860 | 0.70 | EPHX2 (0.38) | IGF1REPHX2ALDH1A1LMNAGRM5 | |
| SCHEMBL92807 | 0.68 | EPHX2 (0.42) | IGF1REPHX2ALDH1A1LMNAGRM5 | |
| SCHEMBL6839719 | 0.68 | — | — | |
| SCHEMBL13104755 | 0.68 | — | — | |
| SCHEMBL1233410 | 0.67 | EPHX2 (0.40) | IGF1REPHX2ALDH1A1LMNAGRM5 | |
| SCHEMBL682658 | 0.67 | — | — | |
| SCHEMBL24348141 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198031-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | Merck Patent GmbH (DE) | 2023-06-21 | — | — | EP | disclosed |