Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905487 | 1.00 | BACE1 (0.46) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL1785406 | 0.98 | BACE1 (0.44) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25598485 | 0.82 | BACE1 (0.44) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL789491 | 0.82 | BACE1 (0.44) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19152829 | 0.82 | BACE1 (0.44) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14446953 | 0.81 | KMT2A (0.39) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25922441 | 0.81 | KMT2A (0.39) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL15776545 | 0.81 | BACE1 (0.43) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL15776544 | 0.81 | BACE1 (0.43) | BACE1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9334473 | 0.79 | LMNA (0.37) | BACE1KMT2ACYP1A2ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098876-A1 | CARBONYL SUBSTITUTED DIAZASPIRO COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2023-06-08 | — | — | WO | disclosed |