Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602077 | 0.86 | KDM4E (0.31) | SMN1; SMN2MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL25823774 | 0.83 | HCRTR1 (0.35) | KDM4EHPGDHRH1DRD3HCRTR1 | |
| SCHEMBL25596501 | 0.80 | DRD3 (0.34) | HRH1DRD3HCRTR1HCRTR2 | |
| SCHEMBL25602212 | 0.77 | HRH1 (0.40) | HRH1DRD3 | |
| SCHEMBL25595351 | 0.72 | HRH1 (0.32) | KDM4EHPGDHRH1DRD3HCRTR1 | |
| SCHEMBL25815995 | 0.71 | KDM4E (0.31) | SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL25600414 | 0.69 | HRH1 (0.33) | HRH1DRD3 | |
| SCHEMBL25597203 | 0.68 | DRD3 (0.49) | NPSR1MAPK1HRH1DRD3LMNA | |
| SCHEMBL25593002 | 0.67 | PNMT (0.47) | HRH1DRD3 | |
| SCHEMBL25592128 | 0.66 | DRD3 (0.43) | MAPK1KDM4EHRH1DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |