Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | UGCG | Q16739 | 4/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25601942 | 0.94 | CXCR2 (0.39) | CXCR2PTPN1CYP3A4UGCGPSMB5 | |
| SCHEMBL25599106 | 0.93 | CXCR2 (0.42) | CXCR2PTPN1KIFC1MRGPRX4MME | |
| SCHEMBL25599540 | 0.92 | PTPN1 (0.36) | CXCR2PTPN1CYP3A4UGCGNHERF1 | |
| SCHEMBL25599284 | 0.91 | CXCR2 (0.51) | CXCR2PTPN1KIFC1MRGPRX4MME | |
| SCHEMBL25599374 | 0.91 | CXCR2 (0.51) | CXCR2PTPN1KIFC1MRGPRX4MME | |
| SCHEMBL25599423 | 0.89 | CXCR2 (0.41) | CXCR2PTPN1KIFC1MRGPRX4MME | |
| SCHEMBL25599229 | 0.89 | CXCR2 (0.41) | CXCR2PTPN1KIFC1MRGPRX4MME | |
| SCHEMBL25599235 | 0.88 | CXCR2 (0.40) | CXCR2PTPN1KIFC1MMEACE | |
| SCHEMBL25599570 | 0.87 | CXCR2 (0.40) | CXCR2PTPN1KIFC1MMEACE | |
| SCHEMBL25599003 | 0.85 | CXCR2 (0.40) | CXCR2KIFC1MRGPRX4MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | CXCR2 1205/4885PTPN1 1876/4885KIFC1 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.