Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | CDH1 | P12830 | 1/20 | 0.32 |
| ▸ | TCF4 | P15884 | 1/20 | 0.32 |
| ▸ | TCF7 | P36402 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | UGCG | Q16739 | 1/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25599221 | 0.93 | GPR132 (0.35) | PTPN1GPR132CXCR2TRPV1YAP1 | |
| SCHEMBL25599537 | 0.92 | CXCR2 (0.41) | PTPN1SLC6A4GPR132CXCR2NHERF1 | |
| SCHEMBL25599046 | 0.91 | CXCR2 (0.41) | PTPN1GPR132CXCR2TRPV1YAP1 | |
| SCHEMBL25599487 | 0.89 | GPR132 (0.34) | PTPN1GPR132CXCR2TRPV1IDH1 | |
| SCHEMBL25601942 | 0.85 | CXCR2 (0.39) | PTPN1SLC6A4CXCR2CTNNB1CYP3A4 | |
| SCHEMBL25599106 | 0.84 | CXCR2 (0.42) | PTPN1GPR132CXCR2CTNNB1CYP3A4 | |
| SCHEMBL25599374 | 0.82 | CXCR2 (0.51) | PTPN1GPR132CXCR2CYP3A4UGCG | |
| SCHEMBL25599284 | 0.82 | CXCR2 (0.51) | PTPN1GPR132CXCR2CYP3A4UGCG | |
| SCHEMBL25599235 | 0.82 | CXCR2 (0.40) | PTPN1GPR132CXCR2YAP1 | |
| SCHEMBL25548900 | 0.81 | PTPN1 (0.43) | PTPN1GPR132CXCR2TRPV1NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | PTPN1 1876/4885SLC6A4 1384/4885GPR132 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.