Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.60 |
| ▸ | RELA | Q04206 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060406 | 0.94 | SMN1; SMN2 (0.53) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL21186386 | 0.81 | CYP2D6 (0.63) | LMNASMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL146339 | 0.81 | SMN1; SMN2 (0.69) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL16139782 | 0.78 | KDM4E (0.81) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL13077895 | 0.77 | MAPT (0.49) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL12596886 | 0.77 | SMN1; SMN2 (0.74) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL14278030 | 0.76 | MAPT (0.48) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL121572 | 0.76 | KDM4E (1.00) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL4298781 | 0.76 | RARA (0.64) | KDM4ELMNANFKB1NFKB2RELA | |
| SCHEMBL505728 | 0.74 | KDM4E (0.69) | KDM4ELMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194442-A1 | ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER | Novaled GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |