Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652028 | 0.87 | PIN1 (0.41) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL19694905 | 0.82 | PIN1 (0.46) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL29519632 | 0.82 | PIN1 (0.46) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL23529631 | 0.81 | PIN1 (0.42) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL30440324 | 0.78 | KDM4E (0.48) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL29932506 | 0.78 | KDM4E (0.48) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL23529573 | 0.78 | KDM4E (0.48) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL24981617 | 0.77 | KDM4E (0.39) | KDM4EPIN1ARHTTLMNA | |
| SCHEMBL24980794 | 0.77 | KDM4E (0.41) | KDM4EPIN1ARSMN1; SMN2HTT | |
| SCHEMBL29946658 | 0.77 | KDM4E (0.41) | KDM4EPIN1ARSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098876-A1 | CARBONYL SUBSTITUTED DIAZASPIRO COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2023-06-08 | — | — | WO | disclosed |