Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 15/20 | 0.73 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.73 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.73 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439297 | 1.00 | CLK1 (0.73) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL24588145 | 0.85 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL29699138 | 0.85 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL29699079 | 0.85 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL24588201 | 0.85 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL29492558 | 0.81 | CCNT1 (0.57) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL24588844 | 0.81 | DYRK1A (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL29699124 | 0.81 | DYRK1A (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL23152046 | 0.79 | CLK1 (0.71) | CLK1CDK5CDK5R1RPS6KA5CCNT1 | |
| SCHEMBL30687302 | 0.79 | CLK1 (0.71) | CLK1CDK5CDK5R1RPS6KA5CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |