Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1G | O15355 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.65 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.65 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.65 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557304 | 0.88 | KDM4E (0.65) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL19513260 | 0.81 | ALDH1A1 (0.68) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL2321869 | 0.80 | KDM4E (0.47) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL2559322 | 0.79 | POLB (0.60) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL31358805 | 0.79 | PPM1G (1.00) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL5143410 | 0.78 | PPM1G (0.62) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL28373118 | 0.78 | MEN1 (0.61) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL28373115 | 0.78 | MEN1 (0.61) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL5143408 | 0.78 | PPM1G (0.62) | PPM1GPTPN1PTPN7PTPN5PTPRO | |
| SCHEMBL3030714 | 0.77 | ALDH1A1 (0.50) | PPM1GPTPN1PTPN7PTPN5PTPRO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |