SCHEMBL25601355

SCHEMBL25601355

O=C1CCC(c2noc3c4c(ccc23)CC2(CCNC2)C4)C(=O)N1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 17/20 0.38
CRBN Q96SW2 17/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25601335 0.93 DDB1 (0.41) DDB1CRBN
SCHEMBL25817837 0.83 DDB1 (0.44) DDB1CRBN
SCHEMBL25601473 0.81 DDB1 (0.38) DDB1CRBN
SCHEMBL25601341 0.80 DDB1 (0.40) DDB1CRBN
SCHEMBL25601339 0.79 DDB1 (0.42) DDB1CRBN
SCHEMBL25601340 0.79 DDB1 (0.44) DDB1CRBN
SCHEMBL25601331 0.79 CRBN (0.49) DDB1CRBN
SCHEMBL25601332 0.78 DDB1 (0.42) DDB1CRBN
SCHEMBL25601358 0.77 DDB1 (0.40) DDB1CRBN
SCHEMBL25601346 0.77 DDB1 (0.41) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088406-A1 FUSED IMIDE DERIVATIVE 正大天晴药业集团股份有限公司 2023-05-25 WO disclosed