SCHEMBL25601415

CC1(C)c2cc(C(F)(F)F)ccc2-c2c1c1c(c3ccccc23)OC(c2ccc(N3CCCCC3)cc2)(c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-3)C=C1

nearest known ligand 0.33

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	PDK2	Q15119	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25601570	0.95	PDK2 (0.36)	PDK2
SCHEMBL25601404	0.94	PDK2 (0.35)	PDK2
SCHEMBL25604193	0.93	PDK2 (0.31)	PDK2
SCHEMBL25601671	0.91	PDK2 (0.32)	PDK2
SCHEMBL25844112	0.91	—	—
SCHEMBL26628050	0.89	PDK2 (0.34)	PDK2
SCHEMBL25601414	0.89	PDK2 (0.32)	PDK2
SCHEMBL25601410	0.89	CASR (0.32)	PDK2
SCHEMBL25601557	0.88	PDK2 (0.38)	PDK2
SCHEMBL25601409	0.88	PDK2 (0.31)	PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4270067-A1	PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND GLASSES	Hoya Lens Thailand Ltd. (TH)	2023-11-01	—	—	EP	disclosed
US-20230227717-A1	PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES	HOYA LENS THAILAND LTD. (TH)	2023-07-20	—	—	US	disclosed
EP-4198102-A1	PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES	Hoya Lens Thailand Ltd. (TH)	2023-06-21	—	—	EP	disclosed
EP-4198583-A1	PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES	Hoya Lens Thailand Ltd. (TH)	2023-06-21	—	—	EP	disclosed