SCHEMBL25601404

SCHEMBL25601404

CC1(C)c2ccccc2-c2ccc(C3(c4ccc(N5CCCCC5)cc4)C=Cc4c5c(c6ccccc6c4O3)-c3ccc(C(F)(F)F)cc3C5(C)C)cc21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.35
CHRM5 P08912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25601557 0.95 PDK2 (0.38) PDK2
SCHEMBL25601671 0.94 PDK2 (0.32) PDK2
SCHEMBL25604183 0.94 PDK2 (0.33) PDK2CHRM5
SCHEMBL25601415 0.94 PDK2 (0.33) PDK2
SCHEMBL25601414 0.93 PDK2 (0.32) PDK2
SCHEMBL25601410 0.92 CASR (0.32) PDK2
SCHEMBL25601409 0.92 PDK2 (0.31) PDK2CHRM5
SCHEMBL25713633 0.91 CASR (0.31)
SCHEMBL25713626 0.91 CASR (0.31)
SCHEMBL25601407 0.90 CASR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269532-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-11-01 EP disclosed
EP-4270067-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND GLASSES Hoya Lens Thailand Ltd. (TH) 2023-11-01 EP disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230227717-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-07-20 US disclosed
EP-4198102-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-06-21 EP disclosed
EP-4198583-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES Hoya Lens Thailand Ltd. (TH) 2023-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES NR2E3, CRY1, RPS10 PDK2 2722/4885CHRM5 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.