Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | PDE8A | O60658 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449293 | 0.94 | IDH1 (0.41) | HTR1ADRD2HTR2AHTR7CNR2 | |
| SCHEMBL17449295 | 0.90 | MEN1 (0.42) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL31108761 | 0.90 | MEN1 (0.42) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL24565129 | 0.85 | HTR1A (0.53) | HTR1ADRD2HTR2AHTR7CNR2 | |
| SCHEMBL23028116 | 0.85 | HTR1A (0.53) | HTR1ADRD2HTR2AHTR7CNR2 | |
| SCHEMBL31546858 | 0.81 | CNR2 (0.45) | HTR1ADRD2CNR2CHRNA7PDE8A | |
| SCHEMBL24338764 | 0.81 | MEN1 (0.54) | HTR1ANPC1RAB9AMEN1CYP1A2 | |
| SCHEMBL30174508 | 0.81 | MEN1 (0.54) | HTR1ANPC1RAB9AMEN1CYP1A2 | |
| Bicarbonate SCHEMBL19583807 | 0.81 | POLB (0.41) | CNR2MEN1CYP1A2KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL20266524 | 0.79 | MEN1 (0.53) | NPC1RAB9AMEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | HTR1A 3521/4885DRD2 4447/4885HTR2A 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.