Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20294763 | 0.88 | SMPD1 (0.39) | SMPD1TP53NPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL25626884 | 0.88 | SMPD1 (0.39) | SMPD1TP53MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL25594025 | 0.86 | SMPD1 (0.56) | SMPD1TP53TSHRTDP1ALDH1A1 | |
| SCHEMBL21421699 | 0.84 | SMPD1 (0.37) | SMPD1SMN1; SMN2ALDH1A1THRB | |
| SCHEMBL21404958 | 0.83 | VHL (0.37) | TP53TSHRMAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL21421663 | 0.82 | THRB (0.33) | SMPD1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25930332 | 0.81 | HDAC3 (0.35) | SMPD1TP53TSHRNPSR1CYP1A2 | |
| SCHEMBL19600791 | 0.80 | GAA (0.36) | SMPD1TP53TSHRNPSR1CYP1A2 | |
| SCHEMBL25603625 | 0.80 | PPARA (0.41) | TP53MEN1KMT2AALDH1A1THRB | |
| SCHEMBL27151955 | 0.80 | SMPD1 (0.39) | SMPD1TP53MAPK1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | SMPD1 1813/4885TP53 350/4885TSHR 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.