Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 7/20 | 0.66 |
| ▸ | HPN | P05981 | 2/20 | 0.66 |
| ▸ | USP7 | Q93009 | 2/20 | 0.55 |
| ▸ | CYBB | P04839 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.43 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MSN | P26038 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602305 | 0.89 | NR4A1 (0.72) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL17712445 | 0.82 | HPN (0.76) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL15494257 | 0.80 | HPN (0.71) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL13856218 | 0.80 | NR4A1 (1.00) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL2035383 | 0.80 | HPN (1.00) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL25602307 | 0.77 | USP7 (0.87) | NR4A1HPNUSP7CYBBPOLB | |
| SCHEMBL5993985 | 0.77 | NR4A1 (0.79) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL10036595 | 0.76 | PTPN1 (0.61) | NR4A1HPNUSP7CYBBHSPD1 | |
| SCHEMBL25602301 | 0.76 | USP7 (0.80) | NR4A1HPNUSP7CYBBFPR1 | |
| SCHEMBL25602302 | 0.75 | USP7 (0.57) | NR4A1HPNUSP7CYBBFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672794-B2 | Therapeutic targeting of the BAP1 complex in cancer | NORTHWESTERN UNIVERSITY (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11672794-B2 | Therapeutic targeting of the BAP1 complex in cancer | BAP1, MCL1, STUB1 | NR4A1 3392/4885HPN 1581/4885USP7 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.