Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.77 |
| ▸ | CCNH | P51946 | 15/20 | 0.77 |
| ▸ | CCNK | O75909 | 14/20 | 0.77 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.77 |
| ▸ | CDK2 | P24941 | 14/20 | 0.77 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.77 |
| ▸ | CDK9 | P50750 | 12/20 | 0.77 |
| ▸ | MNAT1 | P51948 | 13/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17150616 | 0.89 | CDK7 (0.70) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL22115126 | 0.87 | CDK7 (1.00) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL29498451 | 0.87 | CDK7 (1.00) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL25602821 | 0.87 | CCNE1 (0.72) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL24840707 | 0.84 | CCNK (1.00) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL25602843 | 0.84 | CCNK (0.68) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL30456603 | 0.83 | CCNK (0.69) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL24839622 | 0.82 | CCNK (1.00) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL25329325 | 0.82 | CDK7 (0.89) | CDK7CCNHCCNKCDK12CCNE1 | |
| SCHEMBL25329327 | 0.82 | CDK7 (0.89) | CDK7CCNHCCNKCDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |