SCHEMBL25604120

SCHEMBL25604120

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nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27104562 0.88 KDM4E (0.37) KDM4E
SCHEMBL20224390 0.88 KDM4E (0.37) KDM4E
SCHEMBL25603953 0.86 KDM4E (0.38) KDM4E
SCHEMBL25000728 0.81 KDM4E (0.31) KDM4E
SCHEMBL26438959 0.80 GPBAR1 (0.32) KDM4E
SCHEMBL20224695 0.77 GPBAR1 (0.33) KDM4E
SCHEMBL27104564 0.77 KDM4E (0.37) KDM4E
SCHEMBL21728970 0.73 BMP1 (0.32) —
SCHEMBL26533468 0.72 KDM4E (0.43) KDM4E
SCHEMBL25603967 0.71 MEN1 (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172910-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS MERSANA THERAPEUTICS, INC. 2023-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172910-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS STING1, CGAS, IFNAR1 KDM4E 2023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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